6D0X
Crystal structure of chimeric H.2140 / K.1210 Fab in complex with circumsporozoite protein NANP3
Summary for 6D0X
Entry DOI | 10.2210/pdb6d0x/pdb |
Related | 6D01 |
Descriptor | 2140 Antibody, heavy chain, 1210 Antibody, light chain, NANP3, ... (6 entities in total) |
Functional Keywords | malaria, antibody, circumsporozoite protein, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 49260.71 |
Authors | Scally, S.W.,Bosch, A.,Imkeller, K.,Wardemann, H.,Julien, J.P. (deposition date: 2018-04-11, release date: 2018-06-13, Last modification date: 2024-10-09) |
Primary citation | Imkeller, K.,Scally, S.W.,Bosch, A.,Marti, G.P.,Costa, G.,Triller, G.,Murugan, R.,Renna, V.,Jumaa, H.,Kremsner, P.G.,Sim, B.K.L.,Hoffman, S.L.,Mordmuller, B.,Levashina, E.A.,Julien, J.P.,Wardemann, H. Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science, 360:1358-1362, 2018 Cited by PubMed: 29880723DOI: 10.1126/science.aar5304 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.849 Å) |
Structure validation
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