6D05

Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; two molecules of parasite ligand, subclass 2.

Summary for 6D05

• Entry DOI: 10.2210/pdb6d05/pdb
• EMDB information: 7785
• Descriptor: Transferrin receptor protein 1, Serotransferrin, Reticulocyte binding protein 2, putative, ... (8 entities in total)
• Functional Keywords: malaria, plasmodium vivax, reticulocyte, invasion, cell invasion
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 499760.53

Authors

Gruszczyk, J.,Huang, R.K.,Hong, C.,Yu, Z.,Tham, W.H. (deposition date: 2018-04-10, release date: 2018-06-20, Last modification date: 2020-07-29)

• Primary citation: Gruszczyk, J.,Huang, R.K.,Chan, L.J.,Menant, S.,Hong, C.,Murphy, J.M.,Mok, Y.F.,Griffin, M.D.W.,Pearson, R.D.,Wong, W.,Cowman, A.F.,Yu, Z.,Tham, W.H.; Cryo-EM structure of an essential Plasmodium vivax invasion complex.; Nature, 559:135-139, 2018; PubMed: 29950717; DOI: 10.1038/s41586-018-0249-1

Experimental method

ELECTRON MICROSCOPY (3.8 Å)