6CWV

Protein Tyrosine Phosphatase 1B A122S mutant

Summary for 6CWV

Entry DOI	10.2210/pdb6cwv/pdb
Descriptor	Tyrosine-protein phosphatase non-receptor type 1, MAGNESIUM ION (3 entities in total)
Functional Keywords	insulin signaling, diabetes, cancer, signaling, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	38477.08
Authors	Hjortness, M.,Zwart, P.,Sankaran, B.,Fox, J.M. (deposition date: 2018-03-31, release date: 2018-10-24, Last modification date: 2023-10-04)
Primary citation	Hjortness, M.K.,Riccardi, L.,Hongdusit, A.,Zwart, P.H.,Sankaran, B.,De Vivo, M.,Fox, J.M. Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases. Biochemistry, 57:6443-6451, 2018 Cited by PubMed: 30289703 DOI: 10.1021/acs.biochem.8b00656 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98002287694 Å)

Structure validation