6CWK

Anti-RTA VHH antibody

Summary for 6CWK

Related6CWG
DescriptorAnti-Ricin antibody, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordsricin binding antibody, immune system
Biological sourceVicugna pacos
Total number of polymer chains1
Total molecular weight15103.62
Authors
Rudolph, M.J.,Mantis, N. (deposition date: 2018-03-30, release date: 2019-01-16)
Primary citation
Rudolph, M.J.,Vance, D.J.,Kelow, S.,Angalakurthi, S.K.,Nguyen, S.,Davis, S.A.,Rong, Y.,Middaugh, C.R.,Weis, D.D.,Dunbrack Jr., R.,Karanicolas, J.,Mantis, N.J.
Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31:277-287, 2018
PubMed: 30265352 (PDB entries with the same primary citation)
DOI: 10.1093/protein/gzy022
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.256 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.175130 2.0% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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