6CUT
Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3S)-isopropylserine bound as the external aldimine
Summary for 6CUT
| Entry DOI | 10.2210/pdb6cut/pdb |
| Descriptor | Tryptophan synthase beta chain 1, (2S,3S)-3-hydroxy-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-methylpentanoic acid (non-preferred name), SODIUM ION, ... (4 entities in total) |
| Functional Keywords | external aldimine, (2s, 3s)-isopropylserine, lyase |
| Biological source | Pyrococcus furiosus |
| Total number of polymer chains | 4 |
| Total formula weight | 171042.95 |
| Authors | Boville, C.E.,Scheele, R.A.,Buller, A.R.,Arnold, F.H. (deposition date: 2018-03-26, release date: 2018-09-26, Last modification date: 2024-03-13) |
| Primary citation | Boville, C.E.,Scheele, R.A.,Koch, P.,Brinkmann-Chen, S.,Buller, A.R.,Arnold, F.H. Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues. Angew. Chem. Int. Ed. Engl., 57:14764-14768, 2018 Cited by PubMed: 30215880DOI: 10.1002/anie.201807998 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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