Crystal structure of BC8B TCR-CD1b-PC complex

Summary for 6CUG

DescriptorT-cell surface glycoprotein CD1b, Beta-2-microglobulin, T-cell receptor alpha variable TRAV9-2 - BC8B TCR, ... (9 entities in total)
Functional Keywordst cell receptor, antigen presenting molecule, cd1b, pc, phosphatidylcholine, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight97241.68
Shahine, A.E.,Rossjohn, J. (deposition date: 2018-03-26, release date: 2019-01-16)
Primary citation
Shahine, A.,Reinink, P.,Reijneveld, J.F.,Gras, S.,Holzheimer, M.,Cheng, T.Y.,Minnaard, A.J.,Altman, J.D.,Lenz, S.,Prandi, J.,Kubler-Kielb, J.,Moody, D.B.,Rossjohn, J.,Van Rhijn, I.
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10:56-56, 2019
PubMed: 30610190 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-07898-0
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2514 0.1% 1.5% 1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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