6CUG

Crystal structure of BC8B TCR-CD1b-PC complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	T-cell surface glycoprotein CD1b	polymer	300	33530.7	1	UniProt (P29016) Pfam (PF16497) Pfam (PF07654)	Homo sapiens (Human)
2	B (B)	Beta-2-microglobulin	polymer	99	11748.2	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (Human)
3	C (D)	T-cell receptor alpha variable TRAV9-2 - BC8B TCR	polymer	207	22726.1	1		Homo sapiens (Human)
4	D (E)	T-cell receptor beta variable TRBV6-2 - BC8B TCR	polymer	245	27598.9	1		Homo sapiens (Human)
5	E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6	F (A)	tetracosyl octadecanoate	non-polymer		621.1	1	Chemie (CUY)
7	G (D)	(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate	non-polymer		760.1	1	Chemie (POV)
8	H (E)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
9	I, J, K, L (A, B, D, E)	water	water		18.0	414	Chemie (HOH)

Sequence modifications

A: 2 - 278 (UniProt: P29016)

PDB	External Database	Details
Gly 279	-	expression tag
Ser 280	-	expression tag
Gly 281	-	expression tag
Leu 282	-	expression tag
Asn 283	-	expression tag
Asp 284	-	expression tag
Ile 285	-	expression tag
Phe 286	-	expression tag
Glu 287	-	expression tag
Ala 288	-	expression tag
Gln 289	-	expression tag
Lys 290	-	expression tag
Ile 291	-	expression tag
Glu 292	-	expression tag
Trp 293	-	expression tag
His 294	-	expression tag
Glu 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	95603.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1637.9
All*	Total formula weight	97241.7

*Water molecules are not included.