6CU7
Alpha Synuclein fibril formed by full length protein - Rod Polymorph
Summary for 6CU7
Entry DOI | 10.2210/pdb6cu7/pdb |
EMDB information | 7618 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | parkinson's disease, synucleinopathy, amyloid aggregation, fibril polymorphism, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 144761.08 |
Authors | Li, B.,Hatami, A.,Ge, P.,Murray, K.A.,Sheth, P.,Zhang, M.,Nair, G.,Sawaya, M.R.,Zhu, C.,Broad, M.,Shin, W.S.,Ye, S.,John, V.,Eisenberg, D.S.,Zhou, Z.H.,Jiang, L. (deposition date: 2018-03-23, release date: 2018-09-12, Last modification date: 2024-03-13) |
Primary citation | Li, B.,Ge, P.,Murray, K.A.,Sheth, P.,Zhang, M.,Nair, G.,Sawaya, M.R.,Shin, W.S.,Boyer, D.R.,Ye, S.,Eisenberg, D.S.,Zhou, Z.H.,Jiang, L. Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9:3609-3609, 2018 Cited by PubMed: 30190461DOI: 10.1038/s41467-018-05971-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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