6CTZ

Structure of the GDP and kanamycin complex of APH(2")-IIia

Summary for 6CTZ

Entry DOI	10.2210/pdb6ctz/pdb
Descriptor	Gentamicin resistance protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	aminoglycoside resistance, kinase, kanamycin, transferase-antibiotic complex, transferase/antibiotic
Biological source	Enterococcus gallinarum
Total number of polymer chains	1
Total formula weight	34813.45
Authors	Smith, C.A.,Vakulenko, S.B. (deposition date: 2018-03-23, release date: 2019-03-27, Last modification date: 2023-10-04)
Primary citation	Smith, C.A.,Toth, M.,Stewart, N.K.,Maltz, L.,Vakulenko, S.B. Structural basis for the diversity of the mechanism of nucleotide hydrolysis by the aminoglycoside-2''-phosphotransferases Acta Crystallogr.,Sect.D, 75:1129-1137, 2019 Cited by DOI: 10.1107/S2059798319015079 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.34 Å)

Structure validation