6CPS
Crystal structure of the bromodomain of human ATAD2 with a disulfide bridge
Summary for 6CPS
Entry DOI | 10.2210/pdb6cps/pdb |
Descriptor | ATPase family AAA domain-containing protein 2, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | disulfide bridge, bromodomain, epigenetics, chromatin reader domain, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15933.00 |
Authors | Glass, K.C.,Eckenroth, B.E.,Carlson, S. (deposition date: 2018-03-14, release date: 2018-12-19, Last modification date: 2023-10-04) |
Primary citation | Gay, J.C.,Eckenroth, B.E.,Evans, C.M.,Langini, C.,Carlson, S.,Lloyd, J.T.,Caflisch, A.,Glass, K.C. Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain. Proteins, 87:157-167, 2019 Cited by PubMed: 30520161DOI: 10.1002/prot.25636 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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