6CNH

Human PRPF4B in complex with Rebastinib

Summary for 6CNH

• Entry DOI: 10.2210/pdb6cnh/pdb
• Descriptor: Serine/threonine-protein kinase PRP4 homolog, 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: kinase, inhibitor, dcc2036, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 41821.23

Authors

Godoi, P.H.C.,Santiago, A.S.,Ramos, P.Z.,Fala, A.M.,Salmazo, A.P.T.,Counago, R.M.,Righetto, G.L.,Silva, P.N.B.,Gileadi, O.,Guimaraes, C.R.W.,Massirer, K.B.,Arruda, P.,Elkins, J.M.,Edwards, A.M.,Structural Genomics Consortium (SGC) (deposition date: 2018-03-08, release date: 2018-03-28, Last modification date: 2023-10-04)

• Primary citation: Godoi, P.H.C.,Santiago, A.S.,Ramos, P.Z.,Silva, P.N.B.,Righetto, G.L.,Guimaraes, C.R.W.,Massirer, K.B.,Arruda, P.,Elkins, J.M.,Edwards, A.M.; Crystal structure of the human PRPF4B in complex with Rebastinib; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)