6CIO

Pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica with lactyl-TPP bound

Summary for 6CIO

Entry DOI	10.2210/pdb6cio/pdb
Related	6CIN 6CIP 6CIQ
Descriptor	PYRUVATE-FERREDOXIN OXIDOREDUCTASE, IRON/SULFUR CLUSTER, 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, ... (7 entities in total)
Functional Keywords	pyruvate:ferredoxin oxidoreductase, thiamine pyrophosphate, coenzyme a, gated electron transfer, oxidoreductase
Biological source	Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Total number of polymer chains	6
Total formula weight	774590.67
Authors	Chen, P.Y.-T.,Drennan, C.L. (deposition date: 2018-02-24, release date: 2018-03-28, Last modification date: 2023-10-04)
Primary citation	Chen, P.Y.,Aman, H.,Can, M.,Ragsdale, S.W.,Drennan, C.L. Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica. Proc. Natl. Acad. Sci. U.S.A., 115:3846-3851, 2018 Cited by PubMed: 29581263 DOI: 10.1073/pnas.1722329115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.003 Å)

Structure validation