6CHB
Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and IOMA
Summary for 6CHB
Entry DOI | 10.2210/pdb6chb/pdb |
Descriptor | Envelope glycoprotein gp41, Envelope glycoprotein gp120, BG18 Heavy Chain, ... (6 entities in total) |
Functional Keywords | env glycoprotein, broadly neutralizing antibodies, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 18 |
Total formula weight | 503413.58 |
Authors | Barnes, C.O.,Bjorkman, P.J. (deposition date: 2018-02-22, release date: 2018-05-02, Last modification date: 2023-10-04) |
Primary citation | Barnes, C.O.,Gristick, H.B.,Freund, N.T.,Escolano, A.,Lyubimov, A.Y.,Hartweger, H.,West, A.P.,Cohen, A.E.,Nussenzweig, M.C.,Bjorkman, P.J. Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope. Nat Commun, 9:1251-1251, 2018 Cited by PubMed: 29593217DOI: 10.1038/s41467-018-03632-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (6.801 Å) |
Structure validation
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