6CH7
XFEL crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
6CH7 の概要
エントリーDOI | 10.2210/pdb6ch7/pdb |
分子名称 | Envelope glycoprotein gp41, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (19 entities in total) |
機能のキーワード | env glycoprotein, broadly neutralizing antibodies, immune system |
由来する生物種 | Human immunodeficiency virus 1 詳細 |
タンパク質・核酸の鎖数 | 6 |
化学式量合計 | 184316.91 |
構造登録者 | |
主引用文献 | Barnes, C.O.,Gristick, H.B.,Freund, N.T.,Escolano, A.,Lyubimov, A.Y.,Hartweger, H.,West, A.P.,Cohen, A.E.,Nussenzweig, M.C.,Bjorkman, P.J. Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope. Nat Commun, 9:1251-1251, 2018 Cited by PubMed: 29593217DOI: 10.1038/s41467-018-03632-y 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.8 Å) |
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