6CFT
Structure of Human alpha-Phosphomannomutase 1 containing mutations R180T and R183I
Summary for 6CFT
| Entry DOI | 10.2210/pdb6cft/pdb |
| Descriptor | Phosphomannomutase 1, MAGNESIUM ION (3 entities in total) |
| Functional Keywords | phosphatase, haloalkanoate dehalogenase superfamily, mutase, isomerase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29735.30 |
| Authors | Ji, T.,Dunaway-Mariano, D.,Allen, K.N. (deposition date: 2018-02-17, release date: 2018-05-09, Last modification date: 2023-10-04) |
| Primary citation | Ji, T.,Zhang, C.,Zheng, L.,Dunaway-Mariano, D.,Allen, K.N. Structural Basis of the Molecular Switch between Phosphatase and Mutase Functions of Human Phosphomannomutase 1 under Ischemic Conditions. Biochemistry, 57:3480-3492, 2018 Cited by PubMed: 29695157DOI: 10.1021/acs.biochem.8b00223 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
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