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6CFN

Crystal Structure of the DNA-free Glucocorticoid Receptor DNA Binding Domain

Summary for 6CFN
Entry DOI10.2210/pdb6cfn/pdb
DescriptorGlucocorticoid receptor, ZINC ION (3 entities in total)
Functional Keywordsdna binding domain, nuclear receptor, glucocorticoid receptor, dna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains8
Total formula weight81093.28
Authors
Frank, F.,Okafor, C.D.,Ortlund, E.A. (deposition date: 2018-02-15, release date: 2018-09-26, Last modification date: 2023-10-04)
Primary citationFrank, F.,Okafor, C.D.,Ortlund, E.A.
The first crystal structure of a DNA-free nuclear receptor DNA binding domain sheds light on DNA-driven allostery in the glucocorticoid receptor.
Sci Rep, 8:13497-13497, 2018
Cited by
PubMed: 30201977
DOI: 10.1038/s41598-018-31812-9
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

222624

數據於2024-07-17公開中

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