6CFK

Crystal structure of the Thermus thermophilus 70S ribosome in complex with D-histidyl-CAM and bound to protein Y (YfiA) at 2.7A resolution

これはPDB形式変換不可エントリーです。

6CFK の概要

• エントリーDOI: 10.2210/pdb6cfk/pdb
• 分子名称: 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (61 entities in total)
• 機能のキーワード: chloramphenicol, antibiotic, inhibitor, ribosome, 70s, ribosome structure, inhibition of translation, peptidyl transferase center, ribosome-inhibitor complex, ribosome/inhibitor
• 由来する生物種: Escherichia coli (strain K12); 詳細
• タンパク質・核酸の鎖数: 106
• 化学式量合計: 4423447.16

構造登録者

Tereshchenkov, A.G.,Dobosz-Bartoszek, M.,Osterman, I.A.,Marks, J.,Sergeeva, V.A.,Kasatsky, P.,Komarova, E.S.,Stavrianidi, A.N.,Rodin, I.A.,Konevega, A.L.,Sergiev, P.V.,Sumbatyan, N.V.,Mankin, A.S.,Bogdanov, A.A.,Polikanov, Y.S. (登録日: 2018-02-15, 公開日: 2018-03-07, 最終更新日: 2023-11-15)

• 主引用文献: Tereshchenkov, A.G.,Dobosz-Bartoszek, M.,Osterman, I.A.,Marks, J.,Sergeeva, V.A.,Kasatsky, P.,Komarova, E.S.,Stavrianidi, A.N.,Rodin, I.A.,Konevega, A.L.,Sergiev, P.V.,Sumbatyan, N.V.,Mankin, A.S.,Bogdanov, A.A.,Polikanov, Y.S.; Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome.; J. Mol. Biol., 430:842-852, 2018; PubMed: 29410130; DOI: 10.1016/j.jmb.2018.01.016

実験手法

X-RAY DIFFRACTION (2.7 Å)