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6CFJ

Crystal structure of the Thermus thermophilus 70S ribosome in complex with histidyl-CAM and bound to mRNA and A-, P-, and E-site tRNAs at 2.8A resolution

This is a non-PDB format compatible entry.
Summary for 6CFJ
Entry DOI10.2210/pdb6cfj/pdb
Descriptor23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (61 entities in total)
Functional Keywordschloramphenicol, antibiotic, inhibitor, ribosome, 70s, ribosome structure, inhibition of translation, peptidyl transferase center, ribosome-inhibitor complex, ribosome/inhibitor
Biological sourceEscherichia coli
More
Total number of polymer chains112
Total formula weight4566533.47
Authors
Primary citationTereshchenkov, A.G.,Dobosz-Bartoszek, M.,Osterman, I.A.,Marks, J.,Sergeeva, V.A.,Kasatsky, P.,Komarova, E.S.,Stavrianidi, A.N.,Rodin, I.A.,Konevega, A.L.,Sergiev, P.V.,Sumbatyan, N.V.,Mankin, A.S.,Bogdanov, A.A.,Polikanov, Y.S.
Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome.
J. Mol. Biol., 430:842-852, 2018
Cited by
PubMed: 29410130
DOI: 10.1016/j.jmb.2018.01.016
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

数据于2024-03-27公开中

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