6CEN
Crystal Structure of WHSC1L1 in Complex with Inhibitor PEP21
Summary for 6CEN
Entry DOI | 10.2210/pdb6cen/pdb |
Descriptor | Histone-lysine N-methyltransferase NSD3, ACE-GLY-VAL-NLE-ARG-ILE-NH2, S-ADENOSYLMETHIONINE, ... (5 entities in total) |
Functional Keywords | histone-lysine n-methyltransferase nsd3, transferase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9BZ95 |
Total number of polymer chains | 2 |
Total formula weight | 27112.05 |
Authors | Boriack-Sjodin, P.A.,Swinger, K.,Farrow, N.A. (deposition date: 2018-02-12, release date: 2018-05-09, Last modification date: 2018-05-23) |
Primary citation | Morrison, M.J.,Boriack-Sjodin, P.A.,Swinger, K.K.,Wigle, T.J.,Sadalge, D.,Kuntz, K.W.,Scott, M.P.,Janzen, W.P.,Chesworth, R.,Duncan, K.W.,Harvey, D.M.,Lampe, J.W.,Mitchell, L.H.,Copeland, R.A. Identification of a peptide inhibitor for the histone methyltransferase WHSC1. PLoS ONE, 13:e0197082-e0197082, 2018 Cited by PubMed: 29742153DOI: 10.1371/journal.pone.0197082 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.61 Å) |
Structure validation
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