6CEB
Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry
Summary for 6CEB
Entry DOI | 10.2210/pdb6ceb/pdb |
EMDB information | 7461 7462 7463 |
Descriptor | Insulin receptor, Insulin A chain, Insulin B chain, ... (9 entities in total) |
Functional Keywords | signaling, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 234314.85 |
Authors | Scapin, G.,Dandey, V.P.,Zhang, Z.,Strickland, C.,Potter, C.S.,Carragher, B. (deposition date: 2018-02-11, release date: 2018-03-14, Last modification date: 2020-07-29) |
Primary citation | Scapin, G.,Dandey, V.P.,Zhang, Z.,Prosise, W.,Hruza, A.,Kelly, T.,Mayhood, T.,Strickland, C.,Potter, C.S.,Carragher, B. Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556:122-125, 2018 Cited by PubMed: 29512653DOI: 10.1038/nature26153 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.7 Å) |
Structure validation
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