6CC8

Crystal structure MBD3 MBD domain in complex with methylated CpG DNA

Summary for 6CC8

• Entry DOI: 10.2210/pdb6cc8/pdb
• Descriptor: Methyl-CpG-binding domain protein 3, methylated CpG DNA, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 32894.55

Authors

Liu, K.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2018-02-06, release date: 2018-04-04, Last modification date: 2023-10-04)

• Primary citation: Liu, K.,Lei, M.,Wu, Z.,Gan, B.,Cheng, H.,Li, Y.,Min, J.; Structural analyses reveal that MBD3 is a methylated CG binder.; Febs J., 286:3240-3254, 2019; PubMed: 30980593; DOI: 10.1111/febs.14850

Experimental method

X-RAY DIFFRACTION (1.95 Å)