6CBU

Crystal structure of C4S3: A computationally designed immunogen to target Carbohydrate-Occluded Epitopes on the HIV envelope

Summary for 6CBU

Entry DOI	10.2210/pdb6cbu/pdb
Descriptor	Acylphosphatase-1, SULFATE ION (3 entities in total)
Functional Keywords	immunogen, hiv-1, gp120, protein design, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	11402.77
Authors	Zhu, C.,Ke, H.M.,Swanstrom, R.,Dokholyan, N.V. (deposition date: 2018-02-05, release date: 2019-02-06, Last modification date: 2023-10-04)
Primary citation	Zhu, C.,Dukhovlinova, E.,Council, O.,Ping, L.,Faison, E.M.,Prabhu, S.S.,Potter, E.L.,Upton, S.L.,Yin, G.,Fay, J.M.,Kincer, L.P.,Spielvogel, E.,Campbell, S.L.,Benhabbour, S.R.,Ke, H.,Swanstrom, R.,Dokholyan, N.V. Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies. Nat Commun, 10:948-948, 2019 Cited by PubMed: 30814513 DOI: 10.1038/s41467-019-08876-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation