6CAX

Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT805

6CAX の概要

• エントリーDOI: 10.2210/pdb6cax/pdb
• 関連するPDBエントリー: 5UPG
• 分子名称: UDP-3-O-acyl-N-acetylglucosamine deacetylase, (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}butanamide, ZINC ION, ... (6 entities in total)
• 機能のキーワード: ssgcid, lpxc, lipid a biosynthesis, structural genomics, seattle structural genomics center for infectious disease, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35646.48

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2018-02-01, 公開日: 2019-02-13, 最終更新日: 2023-10-04)

• 主引用文献: Phan, J.N.,Delker, S.L.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT805; to be published,

実験手法

X-RAY DIFFRACTION (1.25 Å)