6CA9
Crystal structure of Fab PCT64_LMCA (SAR), the least mutated common ancestor of the HIV-1 broadly neutralizing antibody lineage PCT64
Summary for 6CA9
Entry DOI | 10.2210/pdb6ca9/pdb |
Related | 5FEH 6AC6 6AC7 |
Descriptor | PCT64_LMCA Fab light chain, PCT64_LMCA Fab heavy chain, GLYCEROL, ... (5 entities in total) |
Functional Keywords | igg1, antibody, hiv-1, bnab, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 98221.03 |
Authors | Omorodion, O.,Wilson, I.A. (deposition date: 2018-01-29, release date: 2018-06-27, Last modification date: 2023-11-15) |
Primary citation | Rantalainen, K.,Berndsen, Z.T.,Murrell, S.,Cao, L.,Omorodion, O.,Torres, J.L.,Wu, M.,Umotoy, J.,Copps, J.,Poignard, P.,Landais, E.,Paulson, J.C.,Wilson, I.A.,Ward, A.B. Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Rep, 23:3249-3261, 2018 Cited by PubMed: 29898396DOI: 10.1016/j.celrep.2018.05.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.702 Å) |
Structure validation
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