6C9U
Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab)
Summary for 6C9U
Entry DOI | 10.2210/pdb6c9u/pdb |
Descriptor | 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Light chain of Fab 1B2, Heavy chain of Fab 1B2, ... (6 entities in total) |
Functional Keywords | debs, pks, polyketide synthase, 6-deoxyerthronolide b synthase, fab, antibody, phage display, transferase-immune system complex, transferase/immune system |
Biological source | Saccharopolyspora erythraea (Streptomyces erythraeus) More |
Total number of polymer chains | 3 |
Total formula weight | 152046.27 |
Authors | Deis, L.N.,Li, X.,Mathews, I.I.,Khosla, C. (deposition date: 2018-01-28, release date: 2018-05-23, Last modification date: 2023-10-04) |
Primary citation | Li, X.,Sevillano, N.,La Greca, F.,Deis, L.,Liu, Y.C.,Deller, M.C.,Mathews, I.I.,Matsui, T.,Cane, D.E.,Craik, C.S.,Khosla, C. Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module. J. Am. Chem. Soc., 140:6518-6521, 2018 Cited by PubMed: 29762030DOI: 10.1021/jacs.8b02100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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