6C8W

Crystal structure of Aspartate Semialdehyde Dehydrogenase with NADP from Blastomyces dermatitidis

Summary for 6C8W

• Entry DOI: 10.2210/pdb6c8w/pdb
• Descriptor: Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: rossman fold, antifungal inhibitor complex, nadp cofactor, oxidoreductase
• Biological source: Blastomyces gilchristii (Blastomyces dermatitidis)
• Total number of polymer chains: 2
• Total formula weight: 81792.76

Authors

Dahal, G.P.,Viola, R.E. (deposition date: 2018-01-25, release date: 2019-01-30, Last modification date: 2023-10-04)

• Primary citation: Dahal, G.P.,Viola, R.E.; Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase.; Biochem.Biophys.Res.Commun., 503:2848-2854, 2018; PubMed: 30107909; DOI: 10.1016/j.bbrc.2018.08.053

Experimental method