6C8W

Crystal structure of Aspartate Semialdehyde Dehydrogenase with NADP from Blastomyces dermatitidis

6C8W の概要

• エントリーDOI: 10.2210/pdb6c8w/pdb
• 分子名称: Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• 機能のキーワード: rossman fold, antifungal inhibitor complex, nadp cofactor, oxidoreductase
• 由来する生物種: Blastomyces gilchristii (Blastomyces dermatitidis)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 81792.76

構造登録者

Dahal, G.P.,Viola, R.E. (登録日: 2018-01-25, 公開日: 2019-01-30, 最終更新日: 2023-10-04)

• 主引用文献: Dahal, G.P.,Viola, R.E.; Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase.; Biochem.Biophys.Res.Commun., 503:2848-2854, 2018; PubMed: 30107909; DOI: 10.1016/j.bbrc.2018.08.053

実験手法

X-RAY DIFFRACTION (2.6 Å)