6C6M

IgCam3 of human MLCK1

Summary for 6C6M

Entry DOI	10.2210/pdb6c6m/pdb
Descriptor	Myosin light chain kinase, smooth muscle (2 entities in total)
Functional Keywords	igcam mlck1 ibd, cell adhesion
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	34898.90
Authors	Zuccola, H.J.,Turner, J. (deposition date: 2018-01-19, release date: 2019-01-23, Last modification date: 2024-03-06)
Primary citation	Graham, W.V.,He, W.,Marchiando, A.M.,Zha, J.,Singh, G.,Li, H.S.,Biswas, A.,Ong, M.L.D.M.,Jiang, Z.H.,Choi, W.,Zuccola, H.,Wang, Y.,Griffith, J.,Wu, J.,Rosenberg, H.J.,Wang, Y.,Snapper, S.B.,Ostrov, D.,Meredith, S.C.,Miller, L.W.,Turner, J.R. Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis. Nat. Med., 25:690-700, 2019 Cited by PubMed: 30936544 DOI: 10.1038/s41591-019-0393-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation