6C55

Crystal structure of Staphylococcus aureus Ketol-acid Reductosimerrase with hydroxyoxamate inhibitor 3

6C55 の概要

• エントリーDOI: 10.2210/pdb6c55/pdb
• 分子名称: Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total)
• 機能のキーワード: ketol-acid reductoisomerase, inhibitor, oxidoreductase
• 由来する生物種: Staphylococcus aureus (strain bovine RF122 / ET3-1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 77886.90

構造登録者

Kandale, A.,Patel, K.M.,Zheng, S.,You, L.,Guddat, L.W.,Schenk, G.,Schmbri, M.,McGeary, R.P. (登録日: 2018-01-14, 公開日: 2019-01-16, 最終更新日: 2023-10-04)

• 主引用文献: Kandale, A.,Patel, K.M.,Zheng, S.,You, L.,Guddat, L.W.,Schenk, G.,Schmbri, M.,McGeary, R.P.; Design, synthesis, in vitro activity and crystallisation of novel N-isopropyl-N-hydroxyoxamate derivatives as ketol-acid reductoisomerase (KARI) inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (2.09 Å)