6C1Y

mbd of human mecp2 in complex with methylated DNA

Summary for 6C1Y

• Entry DOI: 10.2210/pdb6c1y/pdb
• Descriptor: Methyl-CpG-binding protein 2, 12-mer DNA, UNKNOWN ATOM OR ION (3 entities in total)
• Functional Keywords: mbd, dna methylation, structural genomics, structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 34283.68

Authors

Liu, K.,Bian, C.,Tempel, W.,Wernimont, A.K.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2018-01-05, release date: 2018-02-14, Last modification date: 2023-10-04)

• Primary citation: Lei, M.,Tempel, W.,Chen, S.,Liu, K.,Min, J.; Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.; Biochim Biophys Acta Gene Regul Mech, 1862:194409-194409, 2019; PubMed: 31356990; DOI: 10.1016/j.bbagrm.2019.194409

Experimental method

X-RAY DIFFRACTION (2.3 Å)