6C1Y

mbd of human mecp2 in complex with methylated DNA

6C1Y の概要

• エントリーDOI: 10.2210/pdb6c1y/pdb
• 分子名称: Methyl-CpG-binding protein 2, 12-mer DNA, UNKNOWN ATOM OR ION (3 entities in total)
• 機能のキーワード: mbd, dna methylation, structural genomics, structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 34283.68

構造登録者

Liu, K.,Bian, C.,Tempel, W.,Wernimont, A.K.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (登録日: 2018-01-05, 公開日: 2018-02-14, 最終更新日: 2023-10-04)

• 主引用文献: Lei, M.,Tempel, W.,Chen, S.,Liu, K.,Min, J.; Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.; Biochim Biophys Acta Gene Regul Mech, 1862:194409-194409, 2019; PubMed: 31356990; DOI: 10.1016/j.bbagrm.2019.194409

実験手法

X-RAY DIFFRACTION (2.3 Å)