6C1W
A tethered niacin-derived pincer complex with a nickel-carbon or sulfite-carbon bond in lactate racemase
Summary for 6C1W
| Entry DOI | 10.2210/pdb6c1w/pdb |
| Descriptor | Lactate racemase, (4S)-5-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-4-sulfo-1,4-dihydropyridine-3-carbothioic S-acid, NICKEL (II) ION, ... (7 entities in total) |
| Functional Keywords | lar, nickel transferase, lara, nickel, lactate, lactate racemization, lactate racemase, sulfite, sulfite-bond, pincer, isomerase, cofactor |
| Biological source | Lactobacillus plantarum |
| Total number of polymer chains | 3 |
| Total formula weight | 145172.18 |
| Authors | Fellner, M.,Desguin, B.,Hausinger, R.P.,Hu, J. (deposition date: 2018-01-05, release date: 2018-03-14, Last modification date: 2023-10-04) |
| Primary citation | Rankin, J.A.,Mauban, R.C.,Fellner, M.,Desguin, B.,McCracken, J.,Hu, J.,Varganov, S.A.,Hausinger, R.P. Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism. Biochemistry, 57:3244-3251, 2018 Cited by PubMed: 29489337DOI: 10.1021/acs.biochem.8b00100 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.398 Å) |
Structure validation
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