6C1H

High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing

6C1H の概要

• エントリーDOI: 10.2210/pdb6c1h/pdb
• EMDBエントリー: 7329 7330 7331
• 分子名称: Actin, alpha skeletal muscle, Unconventional myosin-Ib, Calmodulin, ... (5 entities in total)
• 機能のキーワード: mechanochemistry, mechanobiology, structural biology, cytoskeleton, molecular motor, myosin-i, structural protein
• 由来する生物種: Oryctolagus cuniculus (Rabbit); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 312435.88

構造登録者

Mentes, A.,Huehn, A.,Liu, X.,Zwolak, A.,Dominguez, R.,Shuman, H.,Ostap, E.M.,Sindelar, C.V. (登録日: 2018-01-04, 公開日: 2018-01-31, 最終更新日: 2024-03-13)

• 主引用文献: Mentes, A.,Huehn, A.,Liu, X.,Zwolak, A.,Dominguez, R.,Shuman, H.,Ostap, E.M.,Sindelar, C.V.; High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.; Proc. Natl. Acad. Sci. U.S.A., 115:1292-1297, 2018; PubMed: 29358376; DOI: 10.1073/pnas.1718316115

実験手法

ELECTRON MICROSCOPY (3.9 Å)