6C1H
High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Actin, alpha skeletal muscle | polymer | 375 | 41862.6 | 5 | UniProt (P68135) Pfam (PF00022) In PDB | Oryctolagus cuniculus (Rabbit) | Alpha-actin-1 |
2 | P | Unconventional myosin-Ib | polymer | 729 | 84143.9 | 1 | UniProt (Q05096) Pfam (PF00063) Pfam (PF00612) In PDB | Rattus norvegicus (Rat) | Myosin I alpha,MMIa,Myosin heavy chain myr 1 |
3 | R | Calmodulin | polymer | 148 | 16721.3 | 1 | Pfam (PF13499) UniProt (by SIFTS) (P0DP23) In PDB | unidentified | |
4 | A, B, C, D, E | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 5 | Chemie (ADP) | |||
5 | A, B, C, D, E | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) |
Sequence modifications
P: 6 - 728 (UniProt: Q05096)
PDB | External Database | Details |
---|---|---|
Gly 729 | - | expression tag |
Leu 730 | - | expression tag |
Asn 731 | - | expression tag |
Asp 732 | - | expression tag |
Ile 733 | - | expression tag |
Phe 734 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 7 |
Total formula weight | 310178.3 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 2257.5 | |
All* | Total formula weight | 312435.9 |