6BZ1
MEF2 Chimera D83V mutant/DNA complex
Summary for 6BZ1
Entry DOI | 10.2210/pdb6bz1/pdb |
Descriptor | MEF2 CHIMERA, DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(P*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3') (3 entities in total) |
Functional Keywords | mef2, transcription factor, d83v mutant, conformation switch, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 63028.56 |
Authors | |
Primary citation | Lei, X.,Kou, Y.,Fu, Y.,Rajashekar, N.,Shi, H.,Wu, F.,Xu, J.,Luo, Y.,Chen, L. The Cancer Mutation D83V Induces an alpha-Helix to beta-Strand Conformation Switch in MEF2B. J. Mol. Biol., 430:1157-1172, 2018 Cited by PubMed: 29477338DOI: 10.1016/j.jmb.2018.02.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.97 Å) |
Structure validation
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