6BUU
Crystal structure of AKT1 (aa 144-480) with a bisubstrate
Summary for 6BUU
Entry DOI | 10.2210/pdb6buu/pdb |
Related | 6C01 |
Descriptor | RAC-alpha serine/threonine-protein kinase, GLY-ARG-PRO-ARG-THR-THR-ZXW-PHE-ALA-GLU, SULFATE ION, ... (5 entities in total) |
Functional Keywords | akt1, rac-alpha serine/theronine-protein kinase, kinase, phosphorylated tail, semi-synthesis, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 82053.92 |
Authors | Chu, N.,Gabelli, S.B.,Cole, P.A. (deposition date: 2017-12-11, release date: 2018-08-22, Last modification date: 2024-07-10) |
Primary citation | Chu, N.,Salguero, A.L.,Liu, A.Z.,Chen, Z.,Dempsey, D.R.,Ficarro, S.B.,Alexander, W.M.,Marto, J.A.,Li, Y.,Amzel, L.M.,Gabelli, S.B.,Cole, P.A. Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis. Cell, 174:897-907.e14, 2018 Cited by PubMed: 30078705DOI: 10.1016/j.cell.2018.07.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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