6BSL

BMP1 complexed with a reverse hydroxymate - compound 22

Summary for 6BSL

• Entry DOI: 10.2210/pdb6bsl/pdb
• Descriptor: Bone morphogenetic protein 1, THIOCYANATE ION, ZINC ION, ... (6 entities in total)
• Functional Keywords: endopeptidase, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 47123.46

Authors

Gampe, R.,Shewchuk, L. (deposition date: 2017-12-04, release date: 2018-08-08)

• Primary citation: Kallander, L.S.,Washburn, D.,Hilfiker, M.A.,Eidam, H.S.,Lawhorn, B.G.,Prendergast, J.,Fox, R.,Dowdell, S.,Manns, S.,Hoang, T.,Zhao, S.,Ye, G.,Hammond, M.,Holt, D.A.,Roethke, T.,Hong, X.,Reid, R.A.,Gampe, R.,Zhang, H.,Diaz, E.,Rendina, A.R.,Quinn, A.M.,Willette, B.; Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.; ACS Med Chem Lett, 9:736-740, 2018; PubMed: 30034610; DOI: 10.1021/acsmedchemlett.8b00173

Experimental method

X-RAY DIFFRACTION (1.45 Å)