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6BSJ

Structure of HIV-1 RT complexed with an RNA/DNA hybrid sequence non-preferred for RNA hydrolysis

Summary for 6BSJ
Entry DOI10.2210/pdb6bsj/pdb
DescriptorREVERSE TRANSCRIPTASE P66 SUBUNIT, REVERSE TRANSCRIPTASE P51 SUBUNIT, DNA (5'-D(*GP*TP*AP*TP*GP*CP*CP*TP*AP*TP*AP*GP*TP*TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3'), ... (9 entities in total)
Functional Keywordshiv-rt, dna-rna complex, rnase h, viral protein, viral protein-dna-rna complex, viral protein-dna-rna-inhibitor complex, viral protein/dna/rna/inhibitor
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains4
Total formula weight131379.13
Authors
Tian, L.,Kim, M.,Yang, W. (deposition date: 2017-12-03, release date: 2018-01-03, Last modification date: 2022-03-23)
Primary citationTian, L.,Kim, M.S.,Li, H.,Wang, J.,Yang, W.
Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid.
Proc. Natl. Acad. Sci. U.S.A., 115:507-512, 2018
Cited by
PubMed: 29295939
DOI: 10.1073/pnas.1719746115
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.89 Å)
Structure validation

217705

数据于2024-03-27公开中

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