6BSD
DDR1 bound to Dasatinib
Summary for 6BSD
Entry DOI | 10.2210/pdb6bsd/pdb |
Related | 6BRJ |
Descriptor | Epithelial discoidin domain-containing receptor 1, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE (3 entities in total) |
Functional Keywords | kinase, inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 39740.85 |
Authors | Georghiou, G.,Seeliger, M.A. (deposition date: 2017-12-02, release date: 2018-12-05, Last modification date: 2023-10-25) |
Primary citation | Hanson, S.M.,Georghiou, G.,Thakur, M.K.,Miller, W.T.,Rest, J.S.,Chodera, J.D.,Seeliger, M.A. What Makes a Kinase Promiscuous for Inhibitors? Cell Chem Biol, 26:390-399.e5, 2019 Cited by PubMed: 30612951DOI: 10.1016/j.chembiol.2018.11.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.606 Å) |
Structure validation
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