6BSD

DDR1 bound to Dasatinib

Summary for 6BSD

• Entry DOI: 10.2210/pdb6bsd/pdb
• Related: 6BRJ
• Descriptor: Epithelial discoidin domain-containing receptor 1, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE (3 entities in total)
• Functional Keywords: kinase, inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39740.85

Authors

Georghiou, G.,Seeliger, M.A. (deposition date: 2017-12-02, release date: 2018-12-05, Last modification date: 2023-10-25)

• Primary citation: Hanson, S.M.,Georghiou, G.,Thakur, M.K.,Miller, W.T.,Rest, J.S.,Chodera, J.D.,Seeliger, M.A.; What Makes a Kinase Promiscuous for Inhibitors?; Cell Chem Biol, 26:390-399.e5, 2019; PubMed: 30612951; DOI: 10.1016/j.chembiol.2018.11.005

Experimental method

X-RAY DIFFRACTION (2.606 Å)