6BNT
Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide
Summary for 6BNT
| Entry DOI | 10.2210/pdb6bnt/pdb |
| Descriptor | AP-2 complex subunit mu, Insulin receptor substrate 1 (3 entities in total) |
| Functional Keywords | ap2 mu1, irs1, endocytosis |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 37359.33 |
| Authors | Kikuchi, S.,Choi, E.,Yu, H. (deposition date: 2017-11-17, release date: 2018-11-21, Last modification date: 2023-10-04) |
| Primary citation | Choi, E.,Kikuchi, S.,Gao, H.,Brodzik, K.,Nassour, I.,Yopp, A.,Singal, A.G.,Zhu, H.,Yu, H. Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling. Nat Commun, 10:1473-1473, 2019 Cited by PubMed: 30931927DOI: 10.1038/s41467-019-09318-3 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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