6BLF
PDE2 complexed with 2-[6-fluoro-8-methylsulfonyl-9-[(1R)-1-[4-(trifluoromethyl)phenyl]ethyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid
Summary for 6BLF
Entry DOI | 10.2210/pdb6blf/pdb |
Descriptor | cGMP-dependent 3',5'-cyclic phosphodiesterase, [(1S)-6-fluoro-8-(methylsulfonyl)-9-{(1R)-1-[4-(trifluoromethyl)phenyl]ethyl}-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetic acid, ZINC ION, ... (5 entities in total) |
Functional Keywords | phosphodiesterase, inhibitor, complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 88564.03 |
Authors | Su, H.P. (deposition date: 2017-11-10, release date: 2018-11-14, Last modification date: 2024-03-13) |
Primary citation | Su, H.P. Hydrolase complex To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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