6BLF

PDE2 complexed with 2-[6-fluoro-8-methylsulfonyl-9-[(1R)-1-[4-(trifluoromethyl)phenyl]ethyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid

6BLF の概要

• エントリーDOI: 10.2210/pdb6blf/pdb
• 分子名称: cGMP-dependent 3',5'-cyclic phosphodiesterase, [(1S)-6-fluoro-8-(methylsulfonyl)-9-{(1R)-1-[4-(trifluoromethyl)phenyl]ethyl}-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetic acid, ZINC ION, ... (5 entities in total)
• 機能のキーワード: phosphodiesterase, inhibitor, complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88564.03

構造登録者

Su, H.P. (登録日: 2017-11-10, 公開日: 2018-11-14, 最終更新日: 2024-03-13)

• 主引用文献: Su, H.P.; Hydrolase complex; To Be Published,

実験手法

X-RAY DIFFRACTION (2.11 Å)