6BKB
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3A
Summary for 6BKB
Entry DOI | 10.2210/pdb6bkb/pdb |
Descriptor | Fab AR3A heavy chain, Polyprotein, Fab AR3A light chain, ... (6 entities in total) |
Functional Keywords | hcv, broadly neutralizing antibodies, bnabs, e2 core, ighv1-69, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 69673.65 |
Authors | Tzarum, N.,Wilson, I.A.,Law, M. (deposition date: 2017-11-08, release date: 2018-12-26, Last modification date: 2023-10-04) |
Primary citation | Tzarum, N.,Giang, E.,Kong, L.,He, L.,Prentoe, J.,Augestad, E.,Hua, Y.,Castillo, S.,Lauer, G.M.,Bukh, J.,Zhu, J.,Wilson, I.A.,Law, M. Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies. Sci Adv, 5:eaav1882-eaav1882, 2019 Cited by PubMed: 30613781DOI: 10.1126/sciadv.aav1882 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.799 Å) |
Structure validation
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