6BGP

Crystal Structure of Human Calpain-3 Protease Core Mutant-C129A

Summary for 6BGP

• Entry DOI: 10.2210/pdb6bgp/pdb
• Related: 6BDT
• Descriptor: Calpain-3, CALCIUM ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: calcium binding, cysteine protease, calpain, p94, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 178158.87

Authors

Ye, Q.,Campbell, R.L.,Davies, P.L. (deposition date: 2017-10-29, release date: 2018-02-07, Last modification date: 2023-10-04)

• Primary citation: Ye, Q.,Campbell, R.L.,Davies, P.L.; Structures of human calpain-3 protease core with and without bound inhibitor reveal mechanisms of calpain activation.; J. Biol. Chem., 293:4056-4070, 2018; PubMed: 29382717; DOI: 10.1074/jbc.RA117.001097

Experimental method

X-RAY DIFFRACTION (2.75 Å)