6BDT

Crystal Structure of Human Calpain-3 Protease Core Mutant-C129S

Summary for 6BDT

Entry DOI	10.2210/pdb6bdt/pdb
Descriptor	Calpain-3, CALCIUM ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	calcium binding, cysteine protease, calpain, p94, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	178222.87
Authors	Ye, Q.,Campbell, R.L.,Davies, P.L. (deposition date: 2017-10-24, release date: 2018-02-07, Last modification date: 2023-10-04)
Primary citation	Ye, Q.,Campbell, R.L.,Davies, P.L. Structures of human calpain-3 protease core with and without bound inhibitor reveal mechanisms of calpain activation. J. Biol. Chem., 293:4056-4070, 2018 Cited by PubMed: 29382717 DOI: 10.1074/jbc.RA117.001097 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation