6BDT
Crystal Structure of Human Calpain-3 Protease Core Mutant-C129S
Summary for 6BDT
Entry DOI | 10.2210/pdb6bdt/pdb |
Descriptor | Calpain-3, CALCIUM ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | calcium binding, cysteine protease, calpain, p94, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 178222.87 |
Authors | Ye, Q.,Campbell, R.L.,Davies, P.L. (deposition date: 2017-10-24, release date: 2018-02-07, Last modification date: 2023-10-04) |
Primary citation | Ye, Q.,Campbell, R.L.,Davies, P.L. Structures of human calpain-3 protease core with and without bound inhibitor reveal mechanisms of calpain activation. J. Biol. Chem., 293:4056-4070, 2018 Cited by PubMed: 29382717DOI: 10.1074/jbc.RA117.001097 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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