6BD4

Crystal structure of human apo-Frizzled4 receptor

Summary for 6BD4

DescriptorFrizzled-4/Rubredoxin chimeric protein, ZINC ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (7 entities in total)
Functional Keywordsgpcr, frizzled, apo, membrane protein
Biological sourceHomo sapiens (Human)
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Total number of polymer chains1
Total molecular weight51007
Authors
Yang, S.,Wu, Y.,Pu, M.,Chen, Y.,Dong, S.,Guo, Y.,Han, G.Y.,Stevens, R.C.,Zhao, S.,Xu, F. (deposition date: 2017-10-21, release date: 2018-08-22, Last modification date: 2018-09-12)
Primary citation
Yang, S.,Wu, Y.,Xu, T.H.,de Waal, P.W.,He, Y.,Pu, M.,Chen, Y.,DeBruine, Z.J.,Zhang, B.,Zaidi, S.A.,Popov, P.,Guo, Y.,Han, G.W.,Lu, Y.,Suino-Powell, K.,Dong, S.,Harikumar, K.G.,Miller, L.J.,Katritch, V.,Xu, H.E.,Shui, W.,Stevens, R.C.,Melcher, K.,Zhao, S.,Xu, F.
Crystal structure of the Frizzled 4 receptor in a ligand-free state.
Nature, 560:666-670, 2018
PubMed: 30135577 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-018-0447-x
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.249703.1%14.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution