Crystal structure of human apo-Frizzled4 receptor

Summary for 6BD4

DescriptorFrizzled-4/Rubredoxin chimeric protein, ZINC ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (7 entities in total)
Functional Keywordsgpcr, frizzled, apo, membrane protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight51007
Yang, S.,Wu, Y.,Pu, M.,Chen, Y.,Dong, S.,Guo, Y.,Han, G.Y.,Stevens, R.C.,Zhao, S.,Xu, F. (deposition date: 2017-10-21, release date: 2018-08-22, Last modification date: 2018-09-12)
Primary citation
Yang, S.,Wu, Y.,Xu, T.H.,de Waal, P.W.,He, Y.,Pu, M.,Chen, Y.,DeBruine, Z.J.,Zhang, B.,Zaidi, S.A.,Popov, P.,Guo, Y.,Han, G.W.,Lu, Y.,Suino-Powell, K.,Dong, S.,Harikumar, K.G.,Miller, L.J.,Katritch, V.,Xu, H.E.,Shui, W.,Stevens, R.C.,Melcher, K.,Zhao, S.,Xu, F.
Crystal structure of the Frizzled 4 receptor in a ligand-free state.
Nature, 560:666-670, 2018
PubMed: 30135577 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-018-0447-x
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.249703.1%14.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution