6BCU
Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom
This is a non-PDB format compatible entry.
Summary for 6BCU
Entry DOI | 10.2210/pdb6bcu/pdb |
Related | 6BCX |
EMDB information | 7086 |
Descriptor | Serine/threonine-protein kinase mTOR,Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, Regulatory-associated protein of mTOR,Regulatory-associated protein of mTOR, ... (8 entities in total) |
Functional Keywords | pikk, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 1016877.32 |
Authors | Pavletich, N.P.,Yang, H. (deposition date: 2017-10-20, release date: 2017-12-20, Last modification date: 2024-03-13) |
Primary citation | Yang, H.,Jiang, X.,Li, B.,Yang, H.J.,Miller, M.,Yang, A.,Dhar, A.,Pavletich, N.P. Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552:368-373, 2017 Cited by PubMed: 29236692DOI: 10.1038/nature25023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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