6BCM
Structure of a Self-inhibited N475A variant of the Venezuelan Equine Encephalitis Virus (VEEV) nsP2 cysteine protease
Summary for 6BCM
Entry DOI | 10.2210/pdb6bcm/pdb |
Descriptor | Protease nsP2, GLYCEROL, SODIUM ION, ... (4 entities in total) |
Functional Keywords | alphavirus, nsp2, nonstructural protein, cysteine protease, self-inhibited, n475a, s-adenosyl-l-methionine methyltransferase, viral protein |
Biological source | Venezuelan equine encephalitis virus |
Total number of polymer chains | 1 |
Total formula weight | 38505.95 |
Authors | Compton, J.R.,Legler, P.M. (deposition date: 2017-10-20, release date: 2017-11-08, Last modification date: 2023-10-04) |
Primary citation | Compton, J.R.,Mickey, M.J.,Hu, X.,Marugan, J.J.,Legler, P.M. Mutation of Asn-475 in the Venezuelan Equine Encephalitis Virus nsP2 Cysteine Protease Leads to a Self-Inhibited State. Biochemistry, 56:6221-6230, 2017 Cited by PubMed: 29064679DOI: 10.1021/acs.biochem.7b00746 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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